中文摘要：

血管内皮细胞损伤在动脉粥样硬化过程中起重要作用,一氧化氮生成减少是内皮功能损伤的主要标志。C反应蛋白是动脉粥样硬化过程中的炎性标志物,可通过各种机制损伤血管内皮,参与动脉粥样硬化的病理生理过程。深入细致地研究C反应蛋白等心血管危险因素对血管内皮细胞的损伤机制将有助于动脉粥样硬化相关疾病的防治。

英文摘要：

Endothelial dysfunction,characterized by impaired production of nitro oxide,plays very important role in the development of atherosclerosis.C-reactive protein,a biomarker of inflammation in atherosclerosis,may participate in the process of atherosclerosis by different mechanisms.Further researches on cardiovascular risk factors,such as c-reactive protein,will benefit the prevention and treatment of atherosclerotic diseases.