中文摘要：

设计合成了13个未见文献报道的1,5-二取代吡唑基-1，4-戊二烯-3-酮类化合物，其结构经元素分析，^1HNMR，IR确证．初步生物活性测试结果表明，部分化合物有一定的抗烟草花叶病毒（TMV）活性，所有化合物抑菌活性较低．

英文摘要：

In order to find novel anti-TMV and antifungal compounds with high activity and low toxicity, thirteen new 1,5-bis（substituted pyrazol-4-yl）-1,4-pentadien-3-one derivatives were synthesized. Their structures were characterized by IR, ^1H NMR spectra and elemental analysis. Preliminary bioassays indicated that some compounds showed moderate activity against TMV, and all compounds showed weak antifungal activity.