中文摘要：

迟了发作的出血性的膀胱炎( LOHC )的 pathophysiology 不当前是很好的背景这研究的 understood.The 目的是在 LOHC 柱子 allogeneic 的致病分析 ailoimmune 原因论造血的干细胞移植( HSCT ) .Methods A 回顾的学习与免疫者相关的 LOHC 在 11 个病人的医药记录上被执行柱子 allogeneic HSCT 。这些病人的临床的特征，治疗，和结果是 analyzed.Results 发作的中部的时间是在 HSCT (范围 16-150 天) 以后的 42 天， HC 的中部的持续时间是 .All 病人与延长 HC 介绍了超过 35 天的 43 天(范围 29-47 天) 。有复活没与倔强的 HC 在尿 post-therapy.Eleven 病人甚至与 CMV 清理回答到抗病毒的治疗的 cytomegalovirus ( CMV )的证据的九个病人收到了 corticosteroids 的低剂量，所有病人走进完全的 remission.Conclusion 我们的数据建议那 alloimmune 损害涉及 HC 的致病在在最不，一些病人和那特定的治疗可能改进出血性的膀胱炎的临床的结果。

英文摘要：

Background The pathophysiology of late-onset hemorrhagic cystitis （LOHC） is currently not well understood. The aim of this study was to analyze the alloimmune aetiology in the pathogenesis of LOHC post allogeneic hematopoietic stem cell transplantation （HSCT）. Methods A retrospective study was performed on the medical records of 11 patients with immune-related LOHC post allogeneic HSCT. The clinical characteristics, therapy, and outcomes of these patients were analyzed. Results The median time of onset was 42 days after HSCT （range 16-150 days） and the median duration of HC was 43 days （range 29-47 days）. All patients presented with prolonged HC for more than 35 days. Nine patients with evidence of cytomegalovirus （CMV） reactivation did not respond to anti-viral therapy even with CMV clearance in the urine post-therapy. Eleven patients with refractory HC received a low dose of corticosteroids and all patients went into complete remission. Conclusion Our data suggest that alloimmune injury is involved in the pathogenesis of HC in at least some patients and that specific therapy might improve the clinical outcome of hemorrhagic cystitis.