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HLA-DRB1基因多态性与急性髓性白血病的相关性研究
  • ISSN号：0254-5101
  • 期刊名称：《中华微生物学和免疫学杂志》
  • 时间：0
  • 分类：R758.66[医药卫生—皮肤病学与性病学;医药卫生—临床医学]
  • 作者机构：[1]北京大学人民医院,北京大学血液病研究所,造血干细胞移植治疗血液病北京市重点实验室,100044
  • 相关基金：教育部创新团队发展计划基金（IRT0702）;国家杰出青年基金（30725038）
作者： 霍明瑞[1], 郗斌[1], 于燕[1], 刘海燕[1], 黄晓军[1], 李丹[1]
关键词： HLA-DRB1, 急性髓性白血病, 相关性, 基因多态性, PCR-SSP基因分型, 造血系统恶性肿瘤, HLA基因, AML
中文摘要：

急性髓性白血病（acute myelogenous leukemia，AML）是临床常见的一种造血系统恶性肿瘤。关于HLA与AML的相关性研究，由于环境不同、人种不同，各地的报道结果存在一定差异。本文对732例AML患者及2264例正常对照进行了Ⅱ类基因HLA-DRB1的PCR-SSP基因分型研究，探寻与AML相关的HLA基因。

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期刊信息
  • 《中华微生物学和免疫学杂志》
  • 中国科技核心期刊
  • 主管单位:中国科学技术协会
  • 主办单位:中华医学会
  • 主编：
  • 地址：北京市经济技术开发区经海二路38号
  • 邮编：101111
  • 邮箱：cjmia@163.com
  • 电话：010-52245168
  • 国际标准刊号：ISSN：0254-5101
  • 国内统一刊号：ISSN：11-2309/R
  • 邮发代号:2-55
  • 获奖情况:
  • 1995年中华医学会优秀期刊奖,1996年获全国第二届优秀科技期刊奖,中国科协第二届优秀科技期刊奖,中国期刊方阵“双效”期刊
  • 国内外数据库收录:
  • 美国化学文摘（网络版）,荷兰文摘与引文数据库,荷兰医学文摘,美国生物科学数据库,日本日本科学技术振兴机构数据库,中国中国科技核心期刊,中国北大核心期刊（2004版）,中国北大核心期刊（2008版）,中国北大核心期刊（2011版）,中国北大核心期刊（2014版）,中国北大核心期刊（2000版）
  • 被引量:16081