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Rate Acceleration of the Baylis-Hillman Reaction within Microreactors
  • ISSN号:1001-604X
  • 期刊名称:《中国化学:英文版》
  • 时间:0
  • 分类:O621.3[理学—有机化学;理学—化学] TB383[一般工业技术—材料科学与工程]
  • 作者机构:[1]Beijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China, [2]Graduate School, Chinese Academy of Sciences, Beijing 100049, China
  • 相关基金:Project supported by Ministry of Science and Technology of China (No. 2007CB714504), the National Natural Science Foundation of China (Nos. 20875091, 20935005) and Chinese Academy of Sciences.
中文摘要:

基于 microreactors, cyclopent-2-enone 的代表性的 Baylis-Hillman 反应面对咪唑结合了 4-nitrobenzaldehyde 能被操作温度和电场加速。而且,电场在与近似比那高的 5.2 褶层在温度控制下象 4.0 褶层一样在常规容器执行了的率加速第一次支持 Baylis-Hillman 反应被使用。同时, Baylis-Hillman 反应在的产品每次,点能被毛状的 micellar electrokinetic 收集然后决定层析。

英文摘要:

Based on microreactors, the representative Baylis-Hillman reaction of cyclopent-2-enone coupled with 4-nitrobenzaldehyde in the presence of imidazole could be accelerated by manipulating the temperature and electric field. Furthermore, the electric field was used in promoting Baylis-Hillman reaction for the first time with the rate acceleration approximately 5.2-fold higher than that carried out in conventional vessels as well as 4.0-fold under control of temperature. Meanwhile, the products of Baylis-Hillman reaction at every time point could be collected and then determined by capillary micellar electrokinetic chromatography.

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期刊信息
  • 《中国化学:英文版》
  • 主管单位:
  • 主办单位:中国化学会
  • 主编:
  • 地址:上海市枫林路354号中科院上海有机化学研究所
  • 邮编:200032
  • 邮箱:
  • 电话:021-54925243
  • 国际标准刊号:ISSN:1001-604X
  • 国内统一刊号:ISSN:31-1547/O6
  • 邮发代号:4-646
  • 获奖情况:
  • 中国期刊方阵“双高”期刊
  • 国内外数据库收录:
  • 美国化学文摘(网络版),荷兰文摘与引文数据库,美国科学引文索引(扩展库),日本日本科学技术振兴机构数据库,英国英国皇家化学学会文摘
  • 被引量:175