位置：成果数据库 > 期刊 > 期刊详情页
Discovery of Piperidine-Linked Pyridine Analogues as Potent Non-nucleoside HIV-1 Reverse Transcripta
  • ISSN号：1860-7179
  • 期刊名称：ChemMedChem
  • 时间：2013.7.7
  • 页码：1117-1126
  • 相关项目：新型HEPT类HIV-1非核苷类逆转录酶抑制剂的设计、合成与活性研究
作者： Chen Xuwang|Li Yuanyuan|Ding Shufang|Balzarini Jan|Pannecouque Christophe|De Clercq Erik|Liu Huiqing|Liu Xinyong|
同期刊论文项目
新型HEPT类HIV-1非核苷类逆转录酶抑制剂的设计、合成与活性研究
期刊论文 56 会议论文 5
同项目期刊论文
抗艾滋病药物设计新策略:多靶点及多价态结合配体
Arylazolylthioacetanilide. Part 11: Design, synthesis and biological evaluation of 1,2,4-triazole th
Synthesis and biological evaluation of piperidine-substituted triazine derivatives as HIV-1 non-nucl
Discovery of Novel 2-(3-(2-Chlorophenyl) pyrazin-2-ylthio)-N-arylacetamides As Potent HIV-1 Inhibito
Benzimidazole (Benzimidazolone) Heterocycle as A Privileged Scaffold in Antiviral Agents. Mini-Revie
Synthesis and biological evaluation of novel 5-alkyl-2-arylthio-6-((3,4-dihydroquinolin-1(2H)-yl)met
Cosalane and its Analogues: A Unique Class of Anti-HIV Agents
Facile Synthesis of Derivatives of 1,1,3-Trioxo-2H,4H-pyrrolo[1,2-b] [1,2,4,6]thiatriazine: A New He
Arylazolylthioacetanilide. Part 8: Design, synthesis and biological evaluation of Novel 2-(2-(2,4-Di
1,2,3-thiadiazole thioacetanilides. Part 2: Synthesis and biological evaluation of a new series of 2
Design, synthesis, anti-HIV evaluation and molecular modeling of piperidine-linked amino-triazine de
Arylazolyl(azinyl)thioacetanilide. Part 9: Synthesis and biological investigation of thiazolylthioac
Synthesis, drug release and anti-HIV activity of a series of PEGylated zidovudine conjugates
Recent Progress in Small Molecule CCR5 Antagonists as Potential HIV-1 Entry Inhibitors
病毒蛋白的核输入过程:抗HIV-1药物研究的新靶点
亲环素A:艾滋病治疗的潜在靶点
处于临床试验中的小分子趋化因子受体5拮抗剂
小分子CCR5拮抗剂研究进展
New Therapeutic Approaches Targeted at the Late Stages of the HIV-1 Replication Cycle
Xiao Li, Peng Zhan*, Hong Liu, Dongyue Li, Liu Wang , Xuwang Chen, Huiqing Liu, Christophe Pannecouq
The HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors (Part V): Capravirine and Its Analogues. C
Current drug research on PEGylation with small molecular agents
Strategies for the design of HIV-1 non-nucleoside reverse transcriptase inhibitors: lessons from the
Structure-based bioisosterism design, synthesis and biological evaluation of novel 1,2,4-triazin-6-y
Recent Advances of Diaryl Ether Family as HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors
Discovery of novel pyridazinylthioacetamides as potent HIV-1 NNRTIs using a structure-based bioisost
Privileged Scaffolds or Promiscuous Binders: A Glance of Pyrrolo[2,1-f][1,2,4]triazines and Related
结构优化策略在HIV非核苷类逆转录酶抑制剂设计中的应用
Design, synthesis and biological evaluation of novel 3,5-disubstituted-1,2,6-thiadiazine-1,1-dione d
Design, synthesis and biological evaluation of N2, N4-disubstituted- 1,1,3-trioxo-2H,4H-pyrrolo[1,2-
Diwakar Rai,Wenmin Chena, Ye Tian, Xuwang Chen,Peng Zhan, Erik De Clercq, Christophe Pannecouque, Ja
HIV-1 NNRTIs: Structural diversity, pharmacophore similarity, and impliations for drug design
Rationally designed multitarget anti-HIV agents
Synthesis and anti-HIV activity evaluation of novel N1-arylidene-2-[1-(naphthalen-1-yl)-1H-tetrazol-
Targeting Protein-Protein Interactions: A Promising Avenue of Anti-HIV Drug Discovery
Blocking Nuclear Import of Pre-Integration Complex: An Emerging Anti-HIV-1 Drug Discovery Paradigm
HIV-1衣壳蛋白抑制剂的研究进展
Discovery of Dihydro-Alkyloxy-Benzyl-Oxopyrimidines as Promising Anti-Influenza Virus Agents
Recent Advances in the DABOs Family as Potent HIV-1 non-Nucleoside Reverse Transcriptase Inhibitors
Synthesis and Biological Evaluation of 6-Substituted 5-Alkyl-2-(phenylaminocarbonylmethylthio)pyrimi
Recent Advances in DAPYs and Related Analogues as HIV-1 NNRTIs
Functional Roles of Azoles Motif in Anti-HIV Agents
Recent Advances in the Research of 2,3-Diaryl-1,3-thiazolidin-4-one Derivatives as Potent HIV-1 Non-
Multivalent Agents: A Novel Concept and Preliminary Practice in Anti-HIV Drug Discovery
Novel Piperidinylamino-diarylpyrimidine Derivatives with Dual Structural Conformations as Potent HIV
Retroviral Restriction Factors TRIM5 alpha: Therapeutic Strategy to Inhibit HIV-1 Replication
Synthesis and Anti-HIV Evaluation of Novel 1,2,4-triazole Derivatives as Potential Non-nucleoside HI
Synthesis and biological evaluation of pyridazine derivatives as novel HIV-1 NNRTIs
TSG101: A Novel Anti-HIV-1 Drug Target
Synthesis, In Vitro and In Vivo Release Kinetics, and Anti-HIV Activity of A Sustained-Release Prodr
The Development of HEPT-Type HIV Non-Nucleoside Reverse Transcriptase Inhibitors and Its Implication