中文摘要：

目的：探讨医用臭氧腹腔灌洗术治疗自发性细菌性腹膜炎对肝功能及炎症指标影响。方法选择2013年10月-2015年10月我院收治的肝硬化伴自发性细菌性腹膜炎患者82例，将其随机分为观察组42例、对照组40例，对照组给予采用头孢哌酮舒巴坦静注治疗，观察组给予医用臭氧腹腔灌洗＋头孢哌酮舒巴坦钠静注，比较两组治疗前后肝功能及血清炎症各指标变化情况。结果治疗前两组患者肝功能各项指标（ALT、TIBL、PT、ALB）无显著差异（P〉0.05），治疗后两组患者肝功能各项指标均降低（P〈0.05），观察组患者治疗后各项指标改善情况显著优于对照组（P〈0.05）治疗前两组患者血清CRP、PCT、WBC水平无显著差异（P〉0.05），治疗后两组患者血清各指标均显著降低（P〈0.05），观察组患者治疗后血清各指标改善情况显著优于对照组（P〈0.05）；两组患者不良反应发生率无统计学差异（P〉0.05）。结论医用臭氧腹腔灌洗术治疗肝硬化失代偿性自发性细菌性腹膜炎患者有助于患者炎症指标及肝功能的改善，具有显著的临床疗效，值得临床推广运用。

英文摘要：

Objective To investigate influnence of medical ozone peritoneal lavage on liver function and inflammatory index of spontaneous bacterial peritonitis. Methods From October 2013 to October 2015,82 patients of liver cirrhosis with spontaneous bacterial peritonitis in our hospital,randomly divided to observation group （42 cases） and control group （40 cases） and the control group was given cefoperazone sulbactam,the observation group given medical ozone peritoneal lavage combined with cefoperazone sulbactam,compared with two groups of clinical curative effect,before and after the treatment of each index changes. Results There was no significant difference in ALT,ALB,TBIL and PT levels in two groups before threatment （P〈0.05） but the levels of those are remarkably lower than that of observation group after treatment. The difference was statistically significant（P〈0.05）. There was no significant difference in CRP,WBC and PCT levels in the two groups before treatment（P〉0.05）,and the indexes of serum in the observation group were significantly lower than those in the control group （P〈0.05）. Conclusion medical ozone peritoneal lavage in the treatment of liver cirrhosis patients with spontaneous bacterial peritonitis,has significant clinical curative effect,it can help to improve the index of inflammation,and improve the liver function,it is beneficial to clinical application.