中文摘要：

目的探讨医用臭氧腹腔灌洗术治疗自发性细菌性腹膜炎的有效性及安全性。方法选择2013年10月至2015年10月我院收治的肝硬化伴自发性细菌性腹膜炎患者82例,将其随机分为观察组42例、对照组40例,对照组给予头孢哌酮舒巴坦静注治疗,观察组给予医用臭氧腹腔灌洗＋头孢哌酮舒巴坦钠静注,比较两组临床疗效、治疗前后腹水各指标变化情况。结果观察组患者治疗总有效率（83.33%）显著高于对照组（62.50%）,差异具有统计学意义（P〈0.05）;治疗前两组患者腹水CRP、PCT、WBC以及PMN水平无显著差异（P〉0.05）,治疗后两组患者腹水各指标均显著降低（P〈0.05）,观察组患者治疗后腹水各指标改善情况显著优于对照组（P〈0.05）;两组患者不良反应发生率无统计学差异（P〉0.05）。结论医用臭氧腹腔灌洗术治疗肝硬化失代偿性自发性细菌性腹膜炎患者,具有显著的临床疗效,有助于患者炎症指标的改善,治疗安全可靠,值得临床推广运用。

英文摘要：

Objective To investigate the efficacy and safety of medical ozone peritoneal lavage in the treatment of spontaneous bacterial peritonitis. Methods From October 2013 to October 2015,82 patients of liver cirrhosis with spontaneous bacterial peritonitis in our hospital,randomly divided into observation group（ 42 cases） and control group（ 40 cases） and the control group was given cefoperazone sulbactam,the observation group given medical ozone peritoneal lavage combined with cefoperazone sulbactam,compared clinical curative effect of two groups before and after the treatment of ascites of each index changes. Results The total effective rate of observation group（ 83. 33%） was significantly higher than that of the control group（ 62. 50%）,the difference was statistically significant（ P〈0. 05）. There was no significant difference in CRP,WBC,PCT and PMN levels in the two groups before treatment（ P〈0. 05）,and the indexes of ascites in the observation group were significantly lower than those in the control group（ P〈0. 05）,and the improvement of the indexes of the patients in the observation group was significantly better than that in the control group（ P〈0. 05）.Conclusions Medical ozone peritoneal lavage in the treatment of liver cirrhosis patients with spontaneous bacterial peritonitis,has significant clinical curative effect,it can help to improve the index of inflammation,and the treatment is safe and reliable,it is worthy of clinical application.