中文摘要：

目的：复方夏枯草是临床上用于治疗高血压的医院协定处方,降压活性显著,对其石油醚部位降压活性和化学成分进行研究分析。方法：以动物猫为实验对象,研究石油醚部位的降压活性,结合GC-MS方法初步分析了石油醚部位的化学成分。结果：在石油醚部位样品浓度为5.0mg·ml-1,注射剂量为0.1 ml·kg-1条件下,实验猫的收缩压降低67.673 mmHg,舒张压降低59.079 mmHg。通过GC-MS初步确定了石油醚部位中的11种化合物,含量最大的成分分别是邻苯二甲酸二辛酯,十六酸乙酯,（9Z,12Z,15Z）-十八碳三烯酸,2,3-二羟基酯,质量分数分别为29.887%,7.212%,6.676%。结论：复方夏枯草的石油醚部位降压活性良好,其中挥发性成分主要为酯类物质,相对质量分数为50.936%。

英文摘要：

OBJECTIVE In clinic,compound Prunella vulgaris L.was used for the treatment of hypertension.The aim of present study was to investigate the chemical constituents with hypotensive activities from petroleum ether part of compound Prunella vulgaris L..METHODS The cat was used as experimental model to study the hypotensive activity and the chemical constituent of petroleum ether part of compound Prunella vulgaris L.was studied with GC-MS.RESULTS The strong liquor of petroleum ether part stemmed from compound Prunella vulgaris L.was injected into the cat with the concentration of 5.0 mg·ml-1,the dose of 0.1 ml·kg-1,the systolic pressure of the cat decreased 67.673 mmHg,while the diastolic pressure decreased 59.079 mmHg.11 kinds of compounds were identified from petroleum ether part by GC-MS and the main components were bis（2-ethylhexyl）phthalate,hexadecanoic acid,ethyl ester and 9,12,15-octadecatrienoicacid,2,3-dihydroxypropyl ester,（9Z,12Z,15Z）-;while the correspondence quality fraction was 29.887%,7.212%,6.676% respectively.CONCLUSION The petroleum ether part stemmed from compound Prunella vulgaris L.shows excellent hypotensive activity and the volatile component mainly contains esters substance with the correspondence quality fraction at 50.936%.