目的:建立油当归饮片的质量控制方法。方法:采用传统鉴别、薄层鉴别及指纹图谱法研究油当归质量标准;同时根据2005年版中国药典规定的方法对其水分、灰分及浸出物进行测定。结果:油当归饮片性状表面颜色加深,有浓郁的特异芳香气和淡淡的油香味,油当归饮片中水分、总分灰分和浸出物的平均含量分别为7.30%、8.70%和50.90%;化学指纹图谱确定了油当归指纹峰11个,计算出指纹峰以阿魏酸计的含量。结论:建立了油当归多指标成分的定量方法,方法具有可操作性,使药品质量控制更全面。
Objective: To establish the quality standard of oil-processed Radix Angelica sinensis.Methods: Combined traditional identification,TLC and fingerprints of wine-processed Radix Angelica sinensis to control quality of oil-processed Radix Angelica sinensis.And referring to China Pharmacopoeia of 2005 edition,water,ash,and extract were also detected.Results: The content of water,total ash,extract representatively was 7.30%,8.70% and 50.9%.Eleven fingerprint peaks were defined,The eleven common peaks were appointed as fingerprint peaks by analyzing 14 representative samples,all the fingerprint peaks were quantified grounded on the peak of Ferulic acid.and quantified rested on the peak of ferulic acid.Conclusion: A multicomponent quantitative method for oil-processed Radix Angelica sinensis is established.The established method is feasible.The quality control standards of the oil-processed Radix Angelica sinensis is normative,systematic and accurate.