欢迎您！东篱公司
退出
-
申报数据库
-
立项数据库
-
成果数据库
-
项目获奖数据库
中文摘要：
女性肥胖尤其是腹型肥胖可使其生育力降低，育龄期的肥胖妇女大多表现为月经失调、排卵稀发和雄激素过多。肥胖能够导致内分泌改变、影响血清性激素水平、改变其分泌方式和代谢途径及其在靶器官的作用水平，也是引起多囊卵巢综合征、高雄激素和代谢异常的关键因素。性激素分泌紊乱可能是引起肥胖并表现为不同类型和心血管代谢综合征的重要因素，故通过减轻体重可改善性激素紊乱的状况，降低雄激素水平，同时提高肥胖女性生育力。
英文摘要：
Obesity, particularly abdominal obesity phenotype, may impair fertility of the women. The obese women of childbearing age mainly manifest menstrual disorders, oligo-ovulation and hyperandrogenism. Obesity can cause endocrinological changes of the women, alter serum sex hormone levels and change secretion mode and/or metabolism pathway, and action level in target organs of sex hormones. Also, it is a crucial factor to develop PCOS, hyperandrogenism and metabolic abnormalities. The alterations in sex hormone levels may be an important factor of different obesity phenotypes and cardiovascular metabolic syndromes. So, losing weight can improve disorders of sex hormones and decrease androgen level and improve fertility of those obese women.
同期刊论文项目
同项目期刊论文
期刊信息
位置：