近年来研究发现,Tim基因家族在人体免疫应答中发挥着重要的作用。Tim基因可以调节Th1/Th2免疫状态的平衡及相关免疫细胞功能,阻断或激活Tim基因的功能有助于机体免疫功能的调节。此文对Tim基因家族在免疫调节中的作用进行综述。
In recent years, many studies show that Tim gene family play an important role in human immune respouse. Tim gene always regulates the balance of Th1/Th2 immune status and the function of immune cells. This review focuses on the effects of immune regulation about Tim gene family.