中文摘要：

目的 比较人小涎腺与大涎腺CCL28的表达差异，以期探讨CCL28在小涎腺IgA分泌中的作用。方法应用实时荧光定量PCR技术，分别检测13例健康成人唇腺和8N健康成人腮腺标本中CCL28mRNA表达的相对量；然后用SPSS10．0统计软件对数据进行秩和检验。结果CCL28mRNA在人的唇腺中有丰富的表达，并且唇腺中的CCL28mRNA的表达量高于腮腺（P〈0．01）。结论唇腺CCL28表达量显著高于腮腺，说明小涎腺分泌高浓度IgA可能与CCL28高表达有关。

英文摘要：

Objective To compare the expression of CCL28 in minor and major salivary glands and clarify the role it plays in IgA secreting by minor salivary glands in oral cavity. Methods Labial gland and parotid samples were analyzed with real-time fluorescent quantitative PCR assay for CCL28 mRNA. Rank-sum test was used for data analysis using SPSS 10.0 software package. Results CCL28 mRNA was abundantly expressed in labial glands of healthy adults. Its expression was higher than that in parotids （.P〈0.01）. Conclusion The resuits of this article suggest that the expression level of CCL28 in labial glands is remarkably higher than that in parotids, which reminds us that the high concentration of IgA in minor salivary glands may be associated with their high expression of CCL28.