中文摘要：

目的：优选补肾益髓颗粒的最佳提取工艺。方法：采用正交试验的方法,以马钱苷、补骨脂素、异补骨脂素的含量为指标,筛选补肾益髓颗粒中山茱萸、补骨脂的最佳醇提工艺;以淫羊藿苷含量、干膏率为考察指标,筛选最佳水提工艺条件。结果：补肾益髓颗粒中山茱萸、补骨脂的最佳醇提工艺为加入8倍量60%乙醇,提取3次,每次1 h。最佳水提工艺为加10倍量水,提取3次,每次1 h。结论：优选得到的工艺稳定可行。

英文摘要：

Objective：To optimize the extraction technology of Bushen Yisui Granule.Method：An orthogonal test was adopted in this study.The content of loganin,psoralen and isopsoralen was used as index for optimizing the extraction condition with ethanol for Cornus officinalis and Salvia miltiorrhiza.The content of icaiin and the dried decocting rates was used as index for optimizing the extraction condition with water.Result： The best ethanol extraction technology was to extract for 1 h with 8 times of 60% ethanol 3 times.The best water extraction technology was to extract for 1 h with 10 times of water 3 times.Conclusion： The optimized extraction technology was rational and can be used for the extraction process of Bushen Yisui Granule.