本文对纵向数据的线性混合模型,用Fisher得分法得到了参数的M估计(稳健估计),给出了其渐近性质,研究了M估计下异方差的Score检验问题,并对检验统计量的功效进行了模拟,最后通过葡萄糖数据的实例说明了本文方法的有效性.
In this paper,the Fisher scoring method is applied to get M-estimator (robust estimator) in the mixed effects linear model for longitudinal data.Then some score tests for heteroscedasticity based on M-estimator are studied.And the properties of test statistics are investigated through Monte Carlo simulations.At last,the methods and properties are illustrated by the glucose data example