中文摘要：

饥饿激素（ghrelin）是生长激素促分泌素受体的唯一内源性配体,也是唯一可以在外周刺激食欲的激素。ghrelin在机体食欲、体重、胃肠功能、脂肪代谢、葡萄糖代谢及脂类代谢等生理活动的调节中发挥着重要作用。ghrelin的酰基化是与其受体结合产生相应生物学效应的前提。本文系统综述了ghrelin在能量代谢中的作用模式与分子机制。

英文摘要：

Ghrelin is the only endogenous ligand of growth hormone secretagogue receptor（GHSR）,and is also the only appetite-stimulating hormone in the periphery.Ghrelin plays an important role in the regulation of the appetite,weight,gastrointestinal function,fat metabolism,glucose metabolism,and lipid metabolism,ect.The acidylation of ghrelin plays an essential role in producing the biological effects combining with its receptor.The article summarized that the function patterns and molecular mechanisms of ghrelin in energy metabolism.