目的探讨食管癌患者放射治疗前后维医分型与白细胞介素-1β(IL-1β)、白细胞介素-6(IL-6)及肿瘤坏死因子-α(TNF-α)之间的关系。方法对放疗前后120例患者进行维医分型并检测IL-1β、IL-6、TNF-α水平。结果放疗前后维医分型构成比有差异,均以异常黑胆质为主;放疗后IL-6及TNF-α下降(P〈0.05)、IL-1β下降无差异(P〉0.05);放疗后变为异常黑胆质的患者IL-6及TNF-α变化差异有统计学意义(P〈0.01);而放疗后变为非异常黒胆质的IL-6及TNF-α变化差异无统计学意义(P〉0.05)。结论异常黑胆质为放疗前后食管癌患者的主要维医分型;放疗后变为异常黑胆质的患者免疫功能受损更为严重。
Abstract: Objective To explore the relation between Uyghur Traditional Medieine Syndromes and inter leukin (IL)-1β, IL-6,tumor necrosis factor (TNF)-α of patients with radiotherapy. Methods Before and after radiotherapy, 120 patients esop with hageal carcinoma before and after esophageal cancer were grouped cant differences before and after radiotherapy(Pal0.01). The levels ofIL-6, TNF-a of patients reduced significantly changes of A after radiotherapy (P 〈.0.05). II. 1/3 also reduced, but with no significant differences. The bnormal Savda patients has significant difference (P d0.01), but non-abnormal Savda patients has no difference (P)0.05). Conclusion Abnormal Savda is the major Uyghur Traditional Medie ine Syndromes before and after undergoing radiotherapy; the immunologic function of Abnormal Savda pa tients were seriously injuried after radiotherapy.