探讨食管癌患者放射治疗前后维医分型与T细胞亚群之间的关系。对放疗前后120例患者进行维医分型并用流式细胞仪检测T细胞亚群水平。结果显示:雏医分型放疗前:异常黑胆质60例(50%)〉异常黏液质33例(27.5%)〉异常血液质18例(15%)〉异常胆液质9例(7.5%);放疗后:异常黑胆质92例(76.67%)〉异常胆液质15例(12.5%)〉异常血液质9例(7.5%)〉异常黏液质4例(3.33%)。且放疗前后维医分型构成比具有显著差异性(P〈0.01);放疗后CD3、CD4与CD4/CD8下降,CD8升高(P〈0.05);且放疗后变为异常黑胆质的患者T细胞亚群变化更为显著(P〈0.01);而放疗后变为非异常黑胆质的T细胞亚群变化无统计学意义(P〉0.05)。由此表明:异常黑胆质为放疗前后食管癌患者的主要维医分型;放疗后变为异常黑胆质的患者免疫功能受损更为严重。
To explore the relation between Urgur Traditional Medieine Syndromes and T lymphocyte subsets of patients with Esophageal Carcinonm before and after radiotherapy. Before and after radiotherapy, 120 patients with esoptlageal cancer were grouped according to Urgur traditional medicine theories. FCM( flow cytometly) were applied to measure T lymphocyte subsets. The results show that Urgur Traditional Medieine Syndromes Before radiotherapy:Abnormal Savda( 50% ) 〉 Abnormal Belghem ( 27.5 % ) 〉 Abnormal Kanl ( 15 % ) 〉 Abnormal Sapra (7.5 % ) ;After radiotherapy:Abnormal Savda (76.67 % ) 〉 Abnormal Sa- pra( 12.5% ) 〉 Abnormal Kan(7.5% ) 〉 Abnormal Belghem(3.33% ) ;The propm~ion of Urgur Traditional Medieine Syndromes has significant difference ( P 〈 0. 01 ) ; after radiotherapy, The patients CD3 , CD4 , CDJCDs reduce, CDs rise ( P 〈 0. 05 ) than be- fore;The changes of Abnormal Savda patients has significant difference( P 〈 0. 01 ), but non-abnormal Savda patients has no difference(P 〉 0. 05). It is concluded that:Abnormal Savda is the major Urgur Traditional Medieine Syndromes before and after undergoing radiotherapy;the immunologic function of Abnormal Savda patients were seriously injuried after radiotherapy.