综述了杂质对蛋白质晶体生长影响研究领域的进展情况,对可能的杂质来源以及杂质对结晶过程的影响进行了介绍,重点介绍了和结晶蛋白质分子结构相似的杂质分子的影响,包括晶体成核、生长形态、表面形貌、生长动力学、质量等,以及杂质在晶体中的重新分配。
A review of studies on the influence of impurities on protein crystallization is given. The possible sources of impurities and its effect on the protein crystallization are presented. The effects of impurities on protein crystallization, including nucleation, macroscopic morphologies, microscopic surface morphologies, growth rates,kinetics, quality, and repartitioning of impurities are reviewed.