中文摘要：

客观：调查表示在 diet-inducedobesity (DIO ) 和食谱抵抗(医生) 老鼠在基因抵抗。方法： DIO 和医生模型在由相对高的脂肪，蔗糖，和热量的内容的一本食谱喂的 6 个星期以后与男 SDrats 被准备(他饮食)浆液胰岛素的.Body重量，胖团，和集中被测量，并且在脂肪质的织物( WAT )也是的丝毫的 激活proliferator 的receptory-γ(PPAR-γ)基因由 RT-PCR 检测了的表示 ofresistin 和 Peroxisome 。结果：①身体重量，胖团和浆液胰岛素的集中显著地在 DIO 老鼠被增加并且在医生老鼠减少了。表示 ofresistin 和 PPAR γ基因是起来的②在 DIO 调整了组织并且啜在医生组的 ressed，而是表示抵抗在不在在三个组以内的所有样品是可检测的。结论：Resistin 可以用作在肥胖和胰岛素抵抗之间的一个连接，但是单个差别是庞大的。

英文摘要：

Objective： To investigate the expression of resistin gene in diet-induced obesity （DIO） and diet resistance （DR） rats. Methods： DIO and DR models were prepared with male SD rats after 6 weeks feeding by a diet of relatively high fat, sucrose, and caloric content （HE diet）. Body-weight, fat mass, and the concentration of serum insulin were measured, and the expression of resistin and Peroxisome proliferator-activated receptory-7（PPAR-7） gene in whit adipose tissue （WAT） was also detected by RT-PCR. Results： ① Body weight, fat mass and the concentration of serum insulin were significantly increased in DIO rats and decreased in DR rats. ② The expression of resistin and PPAR7 gene was upregulated in DIO group and supressed in DR group, but the expression of resistin was not detectable in all samples within three groups. Conclusion： Resistin may serve as a link between obesity and insulin resistance, but the individual difference is enormous.