研究了南海红树林内生真菌Gx-5的代谢产物。采用反复硅胶柱色谱法、Sephadex LH-20凝胶色谱法等进行分离纯化,并通过理化常数测定和光谱分析鉴定其化学结构。结果表明,从南海红树林内生真菌Gx-5的菌体中分离得到4个代谢产物。经波谱解析,分别为灰黄霉素(1),去氯灰黄霉素(2),7-22-二烯-3-羟基-6,9-氧桥-麦角甾(3),piliformic(4)。所有化合物均首次从南海红树林内生真菌Gx-5中分离得到。
Secondary metabolites of mangrove endophytic fungus No·Gx-5 from the south China sea were studied. The compounds were isolated by column chromatography and identified on the basia of physic-chemical constants and spectral analysis. The result showed four metabolites were obtained and elucidated as griseofulvin (1), declrorogriseofulvin (2), 7, 22-diene-butyl-3-hydroxy-6, 9-epoxy-ergosta (3), piliformic (4). These four metabolites were obtained from endophytic fungus No · Gx-5 for the first time.