坏死性凋亡在多种器官系统疾病的发生发展中起着关键作用。神经元死亡常见于各类神经系统疾病。近来发现,坏死性凋亡是神经元死亡的重要方式,抑制其坏死性凋亡可在一定程度上实现神经保护作用,也是今后神经系统疾病防治研究的重点。
Necroptosis plays crucial roles in the genesis and development of many diseases involving different organ- isms and systems. Neuronal damage is common in all kinds of neurological diseases. According to recent reports, necroptosis is an important pattern of neuronal death. Inhibition of neuronal necroptosis shows protective roles in neurological diseases. Therefore, studies on neuronal necroptosis will be the focus of prevention and treatment of neurological diseases in the future.