中文摘要：

攻击行为的发生具有重要的遗传学基础。近年来,随着分子遗传学的发展,对攻击行为发生机制的研究已经深入到分子水平,COMT基因成为攻击行为遗传学研究的候选基因之一,然而以人类为被试的研究结论尚存在分歧,甚至相互矛盾。通过回顾、梳理既有关于COMT基因多态性与个体攻击行为关系的研究,剖析了研究结论尚存在分歧和矛盾的原因,并在此基础上从SNP标记、被试群体、研究设计、神经生物机制等几个方面展望了未来研究的方向。

英文摘要：

The development of aggressive behavior has important genetic underpinning.With the advancement of molecular genetics,research on the mechanism underlying aggressive behavior has extended to the molecular level in recent years.A number of studies have identified the COMT （Catechol-O-methyltransferase） gene as one of the candidate genes related to aggressive behavior.However,research findings on human subjects have not been always consistent and even contradictory in some cases.This paper reviewed the recent literature about the effect of the COMT gene on aggressive behavior and analyzed causes of the inconsistencies of research findings.Finally,directions of future research were discussed.