中文摘要：

矿物粉尘是大气颗粒物的重要组成部分,与呼吸系统和心血管系统空气污染疾病密切相关。纳米颗粒物由于微尺度效应、高比表面积和复杂的化学构成具有与常规物质不同的活性。通过研究超细大气颗粒物的表面电性、表面基团、矿物-生物化学作用、体外生物溶解界面反应及自由基等方面的运动与沉降颗粒物的有机-无机体系的界面反应机理及其生物活性的现状与方向,进而指出应从微观体系界面反应的模拟和实验等角度重点揭示其化学-生物活性和毒性,以多学科联合方式对天然超细矿物颗粒物的生物活性进行深入研究。

英文摘要：

Mineral dusts are important components of atmospheric particles, which are closely related to the diseases of respiratory system and cardiovascular system. Because of the micro scale effect, high specific surface area and complex chemical composition, nano particles have different activity with conventional materials. By analyzing the surface electrical property of PM groups, surface groups, mineral-biochemistry action, in vitro biological dissolution reaction on interface, and researches about free radicals, the interface reaction mechanism of organic-inorganic system of particulate, the authors suggested that the chemical-biological activity and toxicity of PM should be revealed from simulation and experiments of micro-system interface reaction in the future. And multidisciplinary should be integrated in further to study the biologic activity of natural ultrafine mineral particles.