中文摘要：

代谢组学是继基因组学、转录组学、蛋白质组学之后系统生物学的主要研究平台，并逐渐成为生命科学的研究热点。在辅助生殖技术（assisted reproductive technology，ART）领域，卵泡液代谢组学已取得较大进展。目前，国内外大多数回顾性研究表明卵泡液相关代谢物（糖类、脂肪酸、氨基酸、激素等）可预测卵母细胞发育潜能，但有待大样本、多中心随机对照试验进一步证实。卵泡液代谢组学的深入研究有望成为评估卵母细胞质量并改善ART,#疗结局的重要方法和手段。

英文摘要：

Following the genomics, transcriptomics and proteomics, metabonomics is becoming a focus of systems biology and a hotspot of life science research. In assisted reproductive technology （ART）, follicular fluid （FF） metabonomics has obtained great progress. At present, most of the retrospective studies have found FF related metabolites （sugars, fatty acids, amino acids, hormones, etc.） can predict oocyte development potential, but clinical research needs to be further confirmed by using multi-center and randomized observation with expanding samples. In-depth study ofFF metabonomics is expected to become the important approach and method of evaluating the oocyte quality and improving the treatment outcome of the ART.