近红外荧光因其更好的组织穿透能力,更低的背景干扰,在超灵敏活体成像以及多光谱生物成像应用中具有明显优势。文章根据量子点的组分以及结构信息,综述了近年来量子点近红外调控的研究进展,并对基于结构以及组分相结合的复合调控,及其无毒近红外量子点发展进行了展望。
Near-infrared(NIR) fl uorescence is superior for in vivo ultrasensitive and multiplex biological imaging because it could provide much higher imaging depth and signal-to-noise ratio than visible fluorescence. Here we reviewed the research progress of composition-dependent and structure-dependent NIR-emitting quantum dots(QDs). Furthermore, the multiple tuning of NIR fl uorescence spectrum and the development of non-toxic QDs were pointed out.