对原核生物基因组的研究显示,基因组GC含量与基因组大小和氧气偏好性等因素存在着一定的相关性。为了探索基因组大小与GC含量的相关性是否受原核生物生活习性的影响,选取了有代表性的411种原核生物(包括古细菌与真细菌),分别从最适生长温度、氧气偏好性、运动特性、水生特性和寄生特性等因素进行分析,发现基因组大小与GC含量的相关性确实受这些因素的影响,而寄生原核生物中显示出最好的相关性。
Researches of prokaryotic genomes have led to the discovery of the correlation of genomic GC content with genome size and aerobics/anaerobics.In order to study the influence of lifestyle of prokaryotes on the correlation between genome size and genomic GC content,we analyzed the effect of optimal growth temperature,aerobics/anaerobics,motility,aquatics,and parasitism,using data from 411 representative prokaryotic species(including archaea and bacteria) and correlation/regression approaches.The results show that the correlation between genome size and genomic GC content is indeed influenced by these factors.Moreover,it was found that the correlation is the most significant in parasitic prokaryotes.