位置:成果数据库 > 期刊 > 期刊详情页
114例HBsAg阳性孕妇及其新生儿PBMC感染HBV的状况
  • ISSN号:1005-4057
  • 期刊名称:广东医学院学报
  • 时间:0
  • 页码:4393-4395
  • 语言:中文
  • 分类:R512.62[医药卫生—临床医学;医药卫生—内科学]
  • 作者机构:[1]广东医学院预防医学教研室,广东湛江524023, [2]山西医科大学流行病学教研室,山西太原030001, [3]广州市疾病预防控制中心,广东广州510080
  • 相关基金:国家自然科学基金资助(30070669)
  • 相关项目:Toll样受体3与HBV宫内感染关系的分子流行病学研究
中文摘要:

目的;了解HBsAg阳性孕妇及其新生儿PBMC HBV感染状况。方法:采用原位杂麦(ISH)技术检测114例孕妇和新生儿PBMC涂片中HBV DNA。结果:114例HBsAg阳性孕妇及其新生儿PBMC HBV DNA的检出率分别为28.07%(32/114)和32.46%(37/114);HBsAg阳性孕妇与其新生儿之间的PBMC HBV感染存在一致性(Kappa=0.52,P〈0.01)。结论:证实HBsAg阳性孕妇与其新生儿之问的PBMC HBV感染存在一致性。

英文摘要:

Objective:To observe the status of HBV infection in peripheral blood mononuclear cells (PBMC) from the HBsAg-positive mothers and their neonates. Methods;In situ hybridization (ISH) was used to detect HBV DNA in PBMC smear from 114 HBsAg-positive mothers and theirs newborns. Results:The positive rates of the PBMC HBV infection of the mothers and their neonates were 28. 07% and 32.46%, respectively. There was an agreement of the HBV infection status between the mothers and their newborns (Kappa=0. 52, P〈 0.01). Conclusion:The result suggests that the HBV infection status from the mothers agrees with that from their newborns.

同期刊论文项目
同项目期刊论文