中文摘要：

目的：初步确立听力正常青年人听觉皮层诱发电位P1-N1-P2各波潜伏期和幅值的参考值并分析其特点。方法：使用澳大利亚HEARLab测试系统,对30例听力正常青年人在三种言语刺激声（/m/、/t/、/g/）、三种刺激强度（55、65、75dB SPL）条件下进行听觉皮层诱发电位P1-N1-P2测试。采用方差分析（ANOVA）评估刺激声频率、刺激声强度以及性别对P1-N1-P2各波潜伏期及幅值的影响。结果：①建立不同言语刺激声、刺激强度下,听力正常青年人听觉皮层诱发电位P1-N1-P2各波潜伏期及幅值的参考值范围;②不同频率言语刺激声（/m/、/t/、/g/）对N1波潜伏期（P〈0.05）、幅值（P〈0.05）以及P2波潜伏期（P〈0.05）均有显著影响;③不同刺激强度（55、65、75dB SPL）对P1-N1-P2各波潜伏期和幅值均无显著影响（P〉0.05）;④N1波的潜伏期和幅值及P2波的潜伏期在部分强度的刺激声下存在性别差异（P〈0.05）。结论：本研究建立了不同言语刺激声、不同刺激强度下听力正常青年人听觉皮层诱发电位P1-N1-P2各波潜伏期和幅值的参考值范围;并发现不同言语刺激声诱发的听觉皮层诱发电位P1-N1-P2特征值呈现各自特性,刺激声频率对N1、P2波特性有显著影响。本研究为该技术在临床的进一步推广应用提供了参考和经验。

英文摘要：

Objective：To explore the normal value and characteristic of cortical auditory evoked potential（P1-N1-P2）in normal hearing young adults.Method：Thirty normal hearing young people were recruited for this study.Cortical auditory evoked potential（P1-N1-P2）was performed at three different speech stimuli（/m/,/t/,/g/）and three different sound intensity（55,65,75 dB SPL）using the Australia HEARLab test system.Analysis of Variance（ANOVA）was used to evaluate the influence of speech stimuli and sound intensity and gender to latency and amplitude of P1-N1-P2.Result：①The normal range of latency and amplitude of P1-N1-P2 for three different speech stimuli and stimuli intensity were established.②There were significant differences among three different speech stimuli for latency（P〈0.05）and amplitude（P〈0.05）of N1 and the latency of wave P2（P〈0.05）.③There were no significant differences among three different stimulus intensity for the amplitude and latency of P1-N1-P2（P〉0.05）.④There were significant differences between gender for amplitude of the wave N1 and P2and the latency of N1（P〉0.05）.Conclusion：We initially acquired the normal range of cortical auditory evoked potential（P1-N1-P2）with different speech stimuli and different stimulus intensities in normal hearing young adults.It is also found that P1-N1-P2 values evoked by different speech stimuli showed diffrenent characteristics and stimulus frequency had a significant influence on N1 and P2wave characteristics.This study provides reference and experience for the further application of this technology in clinical practice.