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含1,2,3-噻二唑的邻甲酰胺基苯甲酰胺类化合物的合成、晶体结构与生物活性
  • 期刊名称：高等学校化学学报，2008, 29(10), 1990-1994
  • 时间：0
  • 分类：O626[理学—有机化学;理学—化学]
  • 作者机构：[1]南开大学元素有机化学国家重点实验室,农药国家工程研究中心,天津300071, [2]中国农业科学院蔬菜花卉研究所,北京100081
  • 相关基金：国家自然科学重点基金（批准号：20432010）资助.
  • 相关项目：生物合理设计绿色农药的分子基础研究
关键词： 邻甲酰胺基苯甲酰胺, 1, 2, 3-噻二唑, 晶体结构, 生物活性, Anthranilic diamides , 1,2,3-Thiadiazole , Crystal structure , Biological activity
中文摘要：

以取代邻氨基苯甲酸为起始原料,设计并合成了一系列未见文献报道的含1,2,3-噻二唑的邻甲酰胺基苯甲酰胺类化合物.所有化合物的结构均经元素分析和^1H NMR确证,并且采用X射线单晶衍射分析方法测定了化合物7g的结构.初步的生物活性试验结果表明,部分化合物具有一定的杀菌活性.

英文摘要：

Since the public introduction of phthalic acid diamides and anthranilic diamides by Nihon Nohyaku, Bayer CropScience and DuPont, respectively, diamides have been the focus of synthesis in the field of agrochemical industry. Especially anthranilic diamides as insecticides, furthermore which also displayed i good herbicidal and fungicidal activities, have recently attracted considerable attention. In the investigation of new agrochemicals, 1,2,3-thiadiazole derivatives often display good biological activities, and some diamides containing 1,2,3-thiadiazole possess good insecticide and fungicidal activities. In order to search for novel diamides which have high activities, a series of novel anthranilic diamides containing 1,2,3-thiadiazole were designed and synthesized, their structures were identified by means of elemental analysis, ^1H NMR, and the structure of compound 7g was determined by X-ray single crystal diffraction method. The preliminary results of biological activity experiment show that some of the title compounds exhibited a favourable fungicidal activity.

同期刊论文项目
生物合理设计绿色农药的分子基础研究
期刊论文 141 会议论文 29
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