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新三取代嘧啶苯磺酰脲衍生物的合成与生物活性
  • 期刊名称：高等学校化学学报，2008, 29(2),319-323
  • 时间：0
  • 分类：O626.41[理学—有机化学;理学—化学]
  • 作者机构：[1]南开大学元素有机化学研究所,元素有机化学国家重点实验室,国家农药工程研究中心,天津300071
  • 相关基金：国家自然科学重点基金（批准号：20432010）资助.
  • 相关项目：生物合理设计绿色农药的分子基础研究
关键词： 磺酰脲, 嘧啶, 除草活性, Sulfonylurea, Pyrimidine, Herbicidal activity
中文摘要：

设计合成了22个具有4，5，6-三取代嘧啶磺酰脲衍生物，其结构经^1H NMR，MS和元素分析确证．经盆栽试验测定了化合物的除草活性，结果表明，嘧啶环5位取代基的引入对分子除草活性有一定的影响．

英文摘要：

In order to develop new herbicidal active compounds and research the structure-activity relationship, twenty-two new sulfonylurea derivatives with trisubstituting group in the pyrimidine ring were designed and synthesized. Their structures were confirmed by ^1H NMR, MS and elemental analysis. Preliminary herbicidal activity of these new sulfonylurea compounds was determined by pot bioassay experiments at dosage of 1.5 kg/ha. The results show that these trisubstituted pyrimidine phenylsulfonylurea derivatives display weak heribicidal activity and the addition of 5-substituting group of the pyrimidine ring affected the herbicidal activity slightly.

同期刊论文项目
生物合理设计绿色农药的分子基础研究
期刊论文 141 会议论文 29
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