中文摘要：

目的：探讨长期服用抗精神病药物的住院精神分裂症患者腹部B超的异常情况及其相关因素,总结临床经验。方法：采用自编的调查量表对2010年8月至2011年7月期间在我院住院的335例慢性精神分裂症患者进行一般情况调查,同时进行腹部B超检查,分析腹部B超结果的阳性率及其相关因素。结果：腹部B超异常结果病例105例（31.3%）,其中脂肪肝78例（23.3%）,占阳性率的74.3%,胆囊结石20例（6.0%）,肝内回声改变13例（3.9%）,胆管结石4例（1.2%）,肝肿瘤1例（0.3%）,肝硬化1例（0.3%）,肾结石7例（2.1%）,肾囊肿2例（0.6%）,附件囊肿2例（0.6%）;腹部B超阳性结果与年龄、体重、服药时间及住院时间呈正相关（P〈0.001）;与性别、职业、病程、疾病类型不相关（P〉0.05）。结论：长期服用抗精神病药物易出现药源性脏器损伤,尤以肝脏最为严重,并可能随年龄、体重、服药时间、住院时间等增长不断加重。应定期检查,及时防治。

英文摘要：

Objective：To explore the abnormalities of long-term use of antipsychotics in schizophrenic inpatients abdominal B ultrasound and its related factors and to make a summary of clinical experience.Methods：Survey Scales self abdominal B ultrasound investigation of 335 cases of chronic schizophrenia patients in our hospital from January 2011 to December,and of different gender,age,occupation,weight,duration of medication time,hospital stay,type of disease investigation and analysis.Results： The cases of abnormal results of abdominal B are 105（31.3%）,among which are 78 cases（23.3%） of fatty liver,74.3% of which are the positive ones.There are 20 cases（6.0%）of gallbladder stones,13 cases（3.9%） of liver within the echo changes,4 cases（1.2%） of bile duct stones,1 case（0.3%） of liver tumor,1 case（0.3%） of cirrhosis,seven cases（2.1%） of kidney stones,two cases of renal cysts（0.6%）,and 2 cases（0.6%） of Annex cysts;The result of abdominal B-positive rate is positively related to（P0.05）one’s gender,job,duration,and type of disease.Conclusions： The long-term use of antipsychotic drugs prone to drug-induced organ damage,especially the most serious in the liver.Maybe it would get worse and worse as one’s age,weight,medication and hospitalization time has been increasing.So such patients should be checked regularly,and get an in-time prevention and treatment.