树突状细胞是体内功能最强的专职抗原呈递细胞。寄生性蠕虫感染不但能促进树突状细胞分化成熟,诱导机体产生Th2型免疫应答,还能抑制树突状细胞正常功能,诱导免疫逃避。本文对树突状细胞在蠕虫感染免疫中的作用进行综述。
Dendritic cells are the strongest professional antigen-presenting cells. Helminth infection could promote maturation of immature dendritic cells, induce Th2-type immune responses, and inhibit the normal function of dendritic cells which is closely associated with the immune evasion. This paper reviews the role of dendritic cells in host immunity against helminth infections.