中文摘要：

目的观察六味补气胶囊等制剂对慢性阻塞性肺疾病（COPD）肺气虚证模型大鼠肺组织中树突状细胞（DC）表达水平影响。方法采用烟熏加LPS气管滴入方法建立COPD肺气虚证实验动物模型,观察经六味补气胶囊治疗后,各组肺组织DC表达水平变化。结果与正常组比较,模型组大鼠肺组织内DC表达的阳性面积增加、平均光密度增强（P〈0.01）;与模型组比较,各治疗组DC阳性面积减小（P〈0.01,P〈0.05）、平均光密度不同程度降低,各治疗组之间未见有统计学差异。结论 COPD肺气虚证模型大鼠肺组织DC表达增加,六味补气胶囊可使这种增加减少。

英文摘要：

Objective To observe the influence of Liuwei Buqi Capsule on the expression of lung dendritic cells （DCs） in rat model of chronic obstructive pulmonary disease （COPD） （type of lung qi deficiency syndrome）. Methods The rat model of COPD （type of lung qi deficiency syndrome） was established by using cigarette smoking and intratracheal instillation of LPS. The expression of lung DCs in all groups was observed after being treated with Liuwei Buqi Capsule. Results The positive area of DCs and average optical density increased in model group compared with those in normal group （P 〈0.01 ）. The positive area of DCs decreased in all treatment groups compared with that in model group （ P 〈 0. 01, P 〈 0.05 ）, and average optical density in all treatment groups decreased to varying degrees. The differences among all treatment groups were not significant. Conclusion The expression of lung DCs in rat model of COPD （type of lung qi deficiency syndrome） increases, which can be reduced by Liuwei Buqi Capsule.