中文摘要：

目的 探讨影响抑郁症患者再入院的危险因素,为抑郁症复发的及时甄别和正确诊治提供科学的临床依据。方法 采用回顾性调查方法,利用电子病历系统收集2012年全年住院患者及三年内的再住院信息,将三年内再次住院作为疾病严重复发的标准,探索三年内再住院的影响因素。由2名具有主治医师及以上职称的临床医生查阅住院现病史、既往史、上级医生查房记录、住院初期的症状体征以及辅助检查等资料。结果 共纳入254例患者,其中38例再住院的患者与216例未再住院的患者在既往住院情况、首发未治间隔（“≤3个月”vs“〉3个月”）、首次发作年龄（“≤45岁”vs“〉45岁”）、确诊后住院次数、既往发作次数方面差异有显著性（P〈0.05）。既往住院次数越多,首发未治间隔越久,患者三年内再住院的风险增大。结论 首次发作与首次治疗的时间间隔长短和再住院呈正相关,既往发作次数及住院次数和再住院之间存在正相关,发作次数越多再住院的风险越高,故对于疾病的早期干预及长期维持治疗有助于降低再入院率。

英文摘要：

Objective To investigate the risk factors of re-hospitalization for depression by case review analysis and provide scientific basis for timely diagnosis and correct treatment of recurrent disease. Method A retrospective survey was conducted to collect information of hospitalized patients in 2012 and re-hospitalization patients within three years. The rehospitalization patients within three years were recruited as criteria for severe disease recurrence to explore the factors influencing re-hospitalization within three years. Two clinicians with the title of primary physician or above were consulted on the history of hospitalization, past medical history, the records of superior doctors, symptoms and signs at the beginning of hospitalization, auxiliary examination and so on. Result A total of 254 patients were enrolled in the study, and 38 patients who were rehospitalized were compared with 216 patients who had not been rehospitalized. There were significant differences in the previous hospitalizations （P〈0.05）, the initial untreated interval （＂≤3months＂ vs ＂〉3months＂）, the first episode age （＂≤45 years old＂ vs ＂〉45 years old＂）, the number of hospitalizations after diagnosis and the number of previous episodes. To use relevant factors as independent variables, two indicators that were ultimately included in the logistic regression model are the number of previous hospitalization and the initial untreated interval. Conclusion The duration of untreated depression and the number of episodes were positively correlated with the re-hospitalization. The previous frequent episode predicted the higher risk of re-hospitalization.