中文摘要：

目的探讨用肾小球滤过率估测值（eGFR）评判的老年高血压及2型糖尿病并发终末期肾病（ESRD）患者血红蛋白（Hb）浓度改变。方法收集高血压及2型糖尿病并发慢性肾病且≥60岁患者230例,将eGFR〈15ml.min-1.1.73m-2（7.80±3.14ml.min-1.1.73m-2）者归为ESRD组,eGFR≥15ml.min-1.1.73m-2（29.76±12.90ml.min-1.1.73m-2）者归为非ESRD组,回顾性比较两组间Hb浓度。结果较非ESRD组〔Hb（100.8±23.0）g/L〕,ESRD组Hb浓度〔（74.4±22.5）g/L〕显著降低（P〈0.05）,且在ESRD与非ESRD组中eGFR均与Hb浓度显著正相关（P〈0.05）。结论eGFR评判的老年高血压及2型糖尿病并发ESRD患者Hb浓度显著降低,且eGFR与Hb浓度具有显著正相关性。

英文摘要：

Objective To study the change of plasma hemoglobin（Hb） concentration in elderly patients with primary hypertension and/or type 2 diabetes （T2DM） complicated with end-stage renal disease（ESRD） determined by estimated glomerular filtration rate（eGFR）.Methods Two hundred thirty cases of patients aged 60 years or older with primary hypertension and/or T2DM complicated with chronic renal disease were enrolled.Patients with chronic renal disease were divided into ESRD group with eGFR less than 15 ml·min-1·1.73 m-2 （7.80±3.14 ml·min-1·1.73 m-2）and non-ESRD group with eGFR not less than 15 ml·min-1·1.73 m-2 〔（29.76±12.90） ml·min-1·1.73 m-2〕.Hb concentration was compared between the above two groups retrospectively.Results Compared with non-ESRD group〔（Hb 100.8 ± 23.0）g/L〕 there was significant decrease in Hb concentration 〔（74.4 ± 22.5）g/L〕 in ESRD group（P0.05）;eGFR was positively related to Hb concentration in ESRD and non-ESRD groups respectively（P0.05,for both）.Conclusions There is significant decrease in Hb concentration in elderly patients with primary hypertension and/or T2DM complicated with ESRD determined by eGFR;eGFR is significantly positively related to Hb concentration.