摘要:本文报道从中国南海湛江硇洲岛海绵Hyatella sp.分离得到5种含氮化合经光谱分析鉴定其结构分别为:环脯氨酰-苏氨酸(1),2-N-(1,3,4-三羟基-17-甲基)十八烷基-2’-羟基-18-甲基二十碳酰胺(2),2-N-(1,3,4-三羟基-17-甲基)十八烷基-2’-羟基-19-甲基二十-碳酰胺(3),2-N-(1,3,4-三羟基-17-甲基)十八烷基-2’-羟基-20-甲基二十二碳酰胺(4)和胸腺嘧啶(5),化合物(1)首次从自然界中发现。
Five compounds with nitrogen have been isolated from Hyatella. sp collected from the Naozhou island of China South Sea and identified as : cyclo (Pro-Thr) ( 1 ), 2-hydroxy-N- ( 1,3,4-trihydroxy-17-methyloctadecan-2-yl-18-methyli- cosanamide (2) ,2-hydroxy-N-( 1,3,4-trihydroxy-17-methyloctadecan-2-yl) -19-methylheneicosanamide (3) ,2-hydroxy- N- ( 1,3,4 -tri-hydroxy- 17 -methyl-octadecan-2-yl) -20-methylbehenamide ( 4 ) and 5 -methyl-pryrimidine-2,4 ( 1 H, 3 H ) - dione (5). Their structures were determined on the basis of chemical evidence and spectral data. Compound 1 was isolated from nature for the first time.