中文摘要：

将基于现代分析技术的代谢组学与蛋白质组学引入酒精性肝病动物模型的评价体系,可极大提高模型评价的准确性、灵敏性和特异性,使评价方法更加科学化,为酒精性肝病发病机制的深入研究及其治疗药物的筛选与开发创造了有利条件。综述近年来基于现代分析技术的代谢组学与蛋白质组学在酒精性肝病动物模型评价中的应用。

英文摘要：

It is helpful in improving the accuracy, sensitivity and specificity of the evaluation methods for animal models of alcoholic liver disease（ ALD）, making them more scientific and promoting the further research on the pathogenesis of ALD and the drug screening and development for the disease that metabo- nomics and proteomics based on modem analytical techniques are introduced into the evaluation system for animal models of ALD. The application of metabonomics and proteomics based on modem analytical techniques in the evaluation on animal models of ALD in recent years was reviewed.