疱疹病毒gC基因属晚期基因.其编码的gC糖蛋白位于成熟病毒粒子囊膜表面,作为重要的结构蛋白参与病毒感染过程。同时,gC糖蛋白还构成病毒粒子表面抗原决定簇,是重要的免疫原,可全面诱导宿主的免疫反应。本文就gC基因及其编码蛋白的特点和相关功能等方面进行总结,以期为疱疹病毒gc基因的深入研究提供有用借鉴。
Herpesvirus gC gene is a late gene that encodes glycoprotein C (gC). The glycoprotein C locates on the surface of virions. As an important structural protein and a major immunogen, gC involves herpesvirus infection and induces protective immune response of the host. This summary reviews expression and functions of gC gene and its encoded protein to provide useful information for the further study of herpesvirus.