中文摘要：

目的：观察结扎肠系膜淋巴管（MLD）对急性失血大鼠红细胞流变性的影响。方法：20只Wistar雄性大鼠随机均分为失血组与结扎组。所有大鼠经右侧颈总动脉匀速放血（失血量为全血量的1/4）,结扎组失血后结扎MLD,失血组仅在MLD下穿线。记录24h存活情况。24h后,将存活大鼠经左侧颈总动脉迅速放血,测定实验前后的红细胞沉降率（ESR）、红细胞电泳、红细胞压积（Hct）,计算红细胞聚集与变形指数。结果：急性失血后24h,结扎组大鼠存活情况（9只）略好于失血组（6只）。急性失血后24h,与实验前相比,失血组与结扎组的ESR、血沉方程K值、校正K值、红细胞电泳时间均显著升高或延长,红细胞变形性降低,失血组的红细胞聚集指数显著升高、红细胞电泳长度与迁移率均显著降低;结扎组的ESR、血沉方程K值、校正K值、红细胞聚集指数、电泳时间较失血组显著降低,红细胞电泳长度与迁移率、变形性较失血组显著升高。结论：急性失血导致大鼠红细胞聚集性升高、红细胞电泳能力及变形性降低,结扎MLD可改善急性失血导致的红细胞流变性异常。

英文摘要：

Objective：To observe the effects of mesenteric lymph duct （MLD） ligation on erythrocyte rheology in acute hemorrhagic rats. Methods： Twenty male Wistar rats were randomly divided into hemorrhage group and ligation group （n=10）. Blood （one fourth of body whole blood volume） was withdrawn through right common carotid arteries after rats were anesthetized. In ligation group, the MLD was ligated after hemorrhage, and only threading under the MLD in hemorrhage group. The survival situation at 24 h was recorded. After 24 h, survival rats were anesthetized again, blood sample was withdrawn through left common carotid artery rapidly. And the erythrocyte sedimentation rate （ESR）, electrophoresis of erythrocytes, hematocrit （Hct） were determined in blood samples of before and after hemorrhage, the erythrocytes aggregation and deformability indices were calculated. Results： It showed that the ligation group survival （9 rats alive） was slightly better than that in hemorrhage group （6 rats alive）. The results of erythrocyte rheology indices showed that the ESR, K value of edquation, K value of emendation and electrophoresis time in hemorrhage group and ligation group were higher or longer than those before hemorrhage, the erythrocyte deformability was reduced significantly, respectively. And the erythrocytes aggregation index in hemorrhage group was increased, the electrophoresis length and migration of erythrocyte in hemorrhage group were lower than those before hemorrhage, respectively. But compared with hemorrhage group, the ESR, K value of edquation, K value of emendation, erythrocytes aggregation index and electrophoresis time in ligation group were lower, the electrophoresis lengh, migration and deformability of erythrocyte were increased significantly. Conclusion： The results indicate that the higher erythrocyte aggregation ability, lower electrophoresis function and deformability are caused by acute hemorrhage in rats, and the MLD ligation can improve the abnormal erythrocyte rheolo