朱西杰教授认为胃癌前病变(PLGC)为病邪对胃黏膜长期反复损伤,导致胃黏膜缺氧增生,最终变性。辨治必须从病邪入手,将"邪"作为治疗靶点,多层次多靶点辨治,祛除病邪乃治疗关键,提出从中医学动态、发展观来认识机体病邪及变化、病邪变化与病位改变、证候转化辨证统一入手,如"旧邪"是导致胃癌前病变重要病因,关键是祛排邪毒,通下最为有效;新燥:旧邪日久,胃阴缺乏,形成新燥,宜酸甘养阴润燥;寒邪:旧邪日久,邪气内停,胃气郁遏,寒从中生胃痛不通,贵在通阳;阴火:脾胃运化失职,元气不足,阳气下陷,阴火上乘,补脾胃,泻阴火,升下陷之阳气为法,创立补脾胃泻阴火升阳汤益胃、升阳、散火;癌邪:复方蜥蜴散,不同微粒和糊剂给药,借以图缓,攻不伤正;通过辨旧邪、新邪和癌邪,祛除有形之邪;辨邪所在位置:邪在胃腑,中焦病,始终抓住一个"衡"字,无论清热泻火、攻下热结、护养胃阴、清化湿热,都以达到脾胃升降平衡,斡旋运化为目的;邪在黏膜,结合胃镜及组织检查,用质地较粘中药研成细粉,口服后附着于胃黏膜表面,防止异物损伤胃黏膜;邪在脉络,根据"久病入络"的思想提出:辛润通络、辛温通络、补益通络、搜风通络等对症方法,因势利导祛邪;最后注重医患相通,调护脾胃,谨防复发。
Professor ZHU Xijie(朱西杰) think PLGC is pathogenic factors injury gastric mucosa for long time, led to gastric mucosa lack of oxygen and hyperplasia, eventually caused degeneration, so Syndrome Differentiation Treatment must from pathogenic, put pathogenic factors become therapeutic target remove harmful pathogenic factors, become the key treatment for the PLGC, put forward the PLGC must from traditional Chinese medicine dynamics and development concept to understand in the body of pathogenic and pathological changes, pathogenic dynamic changes and disease location changes, starting from syndrome transformation, and arguing the old evil is an important reason for PLGC, dispel the evil is important, tongxia is useful; new dry evil: made by old pathogenic, the method is moist; cold pathogens: The blocking of the gas is a reason, the method is tongyang; yin pathogenic: Spleen and stomach dysfunction, Lifting sun be the spirit is method, cancer toxin: use our patent medicine The compound lizards powder to obtain the good effect; debate pathogenic in stomach, balance is important, pathogenic in mucous membrane in combination with gastroscope, use with thick Chinese medicine protection of gastric mucosa; pathogenic in venation, use of the method of tongluo, improve the occasion eliminate pathogenic; pay attention to the doctor-patient communication and regulating spleen and stomach, prevent relapse and various targets the PLGC.