目的:探析奥司他韦联合炎琥宁在小儿病毒性肺炎中的应用,旨在为今后临床用药提供参考依据.方法:前瞻性选取我院2014年7月至2016年10月期间收治的60例小儿病毒性肺炎患儿为研究对象.采用随机数字表法分为2组,对照组给予炎琥宁治疗,观察组给予奥司他韦联合炎琥宁治疗,每组各30例.观察两组患儿临床疗效及不良发应情况.结果:观察组R=0.5278,t=14.161,其可信区间为(0.4516,0.6040),其95%可信区间不包括0.05,差异具有统计学意义;咳痰;咳嗽;肺部啰音消失时间均短于对照组(P〈0.05);观察组不良反应发生率为10.00%明显低于对照组的33.33%(P〈0.05).结论:在小儿病毒性肺炎治疗中给予奥司他韦联合炎琥宁疗效显著,有利于减少不良反应发生情况,值得临床应用与推广.
Objective:To explore the application of oseltamivir combined with Yanhuning in children with viral pneumonia so as to provide reference for future clinical treatment.Methods: 60 cases of children with viral pneumonia admitted in our hospital from Jan.2014 to Oct.2016 were selected as the research object.By randomly all the patients were divided into 2 groups, control the treatment group was given Yanhuning, the observation group was given oseltamivir combined with Yanhuning treatment, 30 cases in each group.The two groups were observed the clinical efficacy and adverse reaction.Results: The observation group R =0.5278, t =14.161, the confidence interval (0.4516, 0.6040), the 95% confidence interval does not include 0.05, the difference was statistically significant;The observation group of patients with wheezing;sputum;cough;pulmonary rales disappeared time was shorter than the control group (P 〈 0.05);The incidence rate of adverse reactions in the observation group was 10.00% significantly lower than 33.33% of the control group (P 〈 0.05).Conclusion: Oseltamivir combined with Yanhuning treatment of children with viral pneumonia can produce a curative effect and can reduce the incidence of adverse reactions.It is worth to have a clinical application and promotion.