中文摘要：

目的：探讨巴贝虫感染的流行病学特点、临床表现、诊断和治疗方法，为巴贝虫病的诊治提供参考。方法回顾性分析1例确诊为田鼠巴贝虫病患者的流行病学资料、临床表现、实验室检查结果、诊断和治疗转归情况。结果田鼠巴贝虫患者主要症状是反复不规则的、可以自限的发热，镜下见骨髓和外周血片红细胞内外有点状、逗点状和环状以及类似疟原虫裂殖体的寄生物；间接免疫荧光检测试验（IFA）阳性，用田鼠巴贝虫特异性引物PCR扩增到阳性条带，序列比对提示为田鼠巴贝虫；磷酸氯喹片联合克林霉素对田鼠巴贝虫病的治疗有效。结论临床上人感染巴贝虫鲜有报道，症状不典型，对发热原因不明时应仔细检查患者骨髓和外周血涂片可以提高诊断率，免疫学（IFA）及 PCR方法检查有助于确诊，田鼠巴贝虫病的治疗有待于进一步探讨。

英文摘要：

Objective To review the epidemiological features, clinical characteristics, diagnosis and treatment of human babesiosis, and to provide the reference for the clinicians.Methods The data of one case with babesia microti-infected were analyzed, retrospectively, including the epidemiological features, clinical ifndings, laboratory test results, treatment and outcomes.Results The main symptoms of human babesiosis was repeatedly irregular self-limited fever. Under microscopy, the parasites display a little bit uncertain forms, such as dots, comma-shaped, ring and parasites looked like plasmodium’ schizonts inside and outside red blood cells of bone marrow and peripheral blood smears. The indirect immunolfuorescent antibody test （IFA） was positive. Positive fragments were ampliifed by PCR using the speciifc primers for babesia microti, and sequence alignment shown the sequense had 99% identity with that of babesia microti. Chloroquine phosphate combined clindamycin were useful to the treatment ofbabesia microti infection. Conclusions Human babesiosis is rarely reported in China with the atypical clinical manifestations. For those patients of unknown origin fever, its necessary to paying more attention to microscopic inspection of bone marrow and peripheral blood smears, which could improve the diagnostic rate of babesiasis and IFA and PCR would help to conifrm it. The treatment of babesia microti infection needs further discussing.