中文摘要：

采用饱和溶液法制备了脱氢枞胺（4-羟基）水杨醛Schiff碱β-环糊精包合物,通过红外光谱、差示扫描量热法（DSC）以及紫外光谱对包合物进行鉴定,并对脱氢枞胺（4-羟基）水杨醛Schiff碱及其包合物的抗癌活性进行了研究。结果表明：脱氢枞胺（4-羟基）水杨醛Schiff碱和环糊精可形成摩尔比为1∶1的包合物;β-环糊精可以将脱氢枞胺（4-羟基）水杨醛Schiff碱在混合溶剂（V（DMSO）∶V（H2O）=1∶1）中的溶解度提高3.4倍;在质量浓度为10μg/mL时,脱氢枞胺（4-羟基）水杨醛Schiff碱及其包合物对卵巢癌细胞株（Hey-1B）的抑制率分别达到50.34%和41.65%。

英文摘要：

Dehydroabietylamine 4-hydroxy-salicylidene Schiff base complexes enwrapped with β-cyclodextrin were prepared by the method of saturation solution,and were identified with IR,DSC and UV.The antitumor activities of the dehydroabietylamine 4-hydroxy-salicylidene Schiff base and the inclusion complexes were studied.The main results were as follows： The inclusion complex was formed at the 1∶1 molar ratio of dehydroabietylamine 4-hydroxy-salicylidene Schiff base and β-cyclodextrin;the solubility of dehydroabietylamine 4-hydroxy salicylidene Schiff base in mixed solvent（V（DMSO）∶V（H2O）=1∶1） was increased by 34 folds after complexing with β-cyclodextrin;the inhibitory ratios of the dehydroabietylamine 4-hydroxy-salicylidene Schiff base and its inclusion complex on ovarian cancer cell line（Hey-1B） were 50.34% and 41.65 %,respectively,at the concentration of 10 μg/mL.