中文摘要：

目的：总结中国人脂溢性角化病的皮肤镜特征，为皮肤镜鉴别诊断色素性皮损提供依据。方法：回顾性分析2009年9月－2011年11月在北京大学第一医院皮肤科行皮肤镜检查并经组织病理确诊的脂溢性角化病皮损的皮肤镜图像。结果：共分析了100例患者的110个脂溢性角化病皮损，最主要的皮肤镜指征按出现频率由高到低，分别为粉刺样开口（63．6％），发卡样血管和沟脊结构（均为42．7％）、粟粒样囊肿（40％）及灰白色粗壮网格样结构（30．9％）。加用皮肤镜后可将肉眼诊断的准确率提高39．1％。结论：“灰白色粗壮网格样结构内衬血管”是脂溢性角化病的一种特异皮肤镜结构，组织病理上对应棘层肥厚型。以临床为基础，使用皮肤镜能明显提高脂溢性角化病的诊断准确率。

英文摘要：

Objective： To summarize the dermoscopic features of seborrheic keratosis （SK） in Chinese in order to provide the basis for differential diagnosis of pigmented dermatoses with dermoscopy. Methods： All dermoscopic images of SK lesions from the database in the department of dermatology, the First Affiliated Hospital of Peking University from September 2009 to November 2011, were retrospectively analyzed. The diagnosis in all cases was pathologically confirmed. Results： The dermoscopic images of 110 SK lesions from 100 patients were analyzed. The main dermoscopic features of SK by frequency, from high to low, were comedo-like openings （63.6%）, hairpin blood vessels and fissures （both 42.7%）, milia-like cysts （40%） and grey-white burly mesh-like structure （30.9%）. The clinical diagnostic accuracy with naked eyes was improved by 39.1% with dermoscopy as compared to no dermoscopy. Conclusions： ＂Grey-white burly mesh-like structure＂ is specific dermoscopic feature for SK, pathologically corresponding to acanthotic type. Based on the clinical data, dermoscopy can significantly improve the diagnostic accuracy of seborrheic keratosis.