中文摘要：

下丘脑在维持能量代谢活动中发挥着关键的作用,下丘脑核团之间通过神经肽形成的调控网络是能量平衡的基础（焦广发等,2010）。下丘脑神经元会分泌一些神经肽,这些神经肽可分为两类：（1）促进食欲神经肽

英文摘要：

Neuropeptide Y （NPY）, agouti related peptide （AgRP）, pro-opiomelanocortin （POMC） and cocaine and am- phetamine regulated transcript peptide （CART） are four neuropeptides that play essential roles in the regulation of food in- take and energy homeostasis in mammals. Partial eDNA sequences of NPY, AgRP, POMC and CART genes were obtained using the RT-PCR method. The obtained partial sequences of NPY, AgRP, POMC, and CART were 162 bp, 187 bp, 240 bp, and 55 bp in length, respectively, which contain open reading frames （ORF） of 114 bp, 179 bp, 214 bp, 54 bp separately. The protein coding of these sequences include 37 amino acids in NPY; 59 amino acids in AgRP; 71 a- mino acids in POMC ; 17 amino acids in CART. A search of the BLAST database showed that the deduced sequence of E. miletus NPY, AgRP, POMC and CART were very similar to the NPY, AgRP, POMC and CART of Rattus norvegicus, Mus musculus, and Acomys russatus. In order to make a further determination of the evolutional position of E. miletus, the NPY, AgRP, POMC and CART genes were used to reconstruct phylogenetic trees by using ML method. The result showed that E. miletus has the closest relationship relative to R. norvegicus and M. museulus. The finding of this comparative study will contribute to further revealing the energy metabolism mechanisms of E. miletus from an evolutionary perspective.