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Bioadaptability: An Innovative Concept for Biomaterials
  • ISSN号:1005-0302
  • 期刊名称:《材料科学技术学报:英文版》
  • 时间:0
  • 分类:Q51[生物学—生物化学] TB3[一般工业技术—材料科学与工程]
  • 作者机构:[1]National Engineering Research Center for Tissue Restoration and Reconstruction, South China University of Technology, Guangzhou 510006, China, [2]School of Materlals Science and Engineering, South China University of Technology, Cuangzhou 510640, China
  • 相关基金:This study was financially supported by the National Basic Research Program of China (No. 2012CB619100).
作者: Yingjun Wang[1,2]
中文摘要:

Biocompatibility 是为织物修理的 biomaterials 的基本要求。然而, biocompatibility 的现在的概念在解释涉及基于 biomaterial 的织物修理的现象有某个限制。新材料,特别地那些因为织物设计和新生,与普通特征被开发了,即他们在在 biomaterials 和纸巾之间的人的身体和相互作用深深地参与进重要化学、生物的过程是更多的建筑群。理解在这些 biomaterials 和纸巾之间的相互影响为他们的发展和 functionalization 是重要的。此处,我们建议 biomaterials 的 bioadaptability 的概念。这个概念描述能在织物修理决定 biomaterials 的表演的三个很重要的方面:1 ) 微型环境的适应性在 situ 由 biomaterials 创造了到本国的微型环境;2 ) 到本国的织物的 biomaterials 的机械性质的适应性;3 ) 到新织物形成的 biomaterials 的降级性质的适应性。bioadaptability 的概念在某个微型环境和分子的机制以内强调材料特征和生物方面。揭开,以促进 biomaterials 的 functionalization 的新想法并且调查 biomaterials 和纸巾的相互作用机制由 biomaterials 在织物修理过程期间发出的基础可以提供新灵感。而且,与如此的 bioadaptability 设计 biomaterials 将为修理并且再生机关或纸巾打开一扇新门。在这评论,我们为织物修理应用在 biomaterials 的 bioadaptability 上在最近的年里总结了工作。

英文摘要:

Biocompatibility is the basic requirement of biomaterials for tissue repair. However, the present concept of biocompatibility has a certain limitation in explaining the phenomena involved in biomaterial-based tissue repair. New materials, in particular those for tissue engineering and regeneration, have been developed with common characteristics, i.e. they participate deeply into important chemical and biological processes in the human body and the interaction between the biomaterials and tissues is far more complex. Understanding the interplay between these biomaterials and tissues is vital for their development and functionalization. Herein, we suggest the concept of bioadaptability of biomaterials. This concept describes the three most important aspects that can determine the performance of biomaterials in tissue repair: 1) the adaptability of the micro-environment created by biomaterials to the native microenvironment in situ; 2) the adaptability of the mechanical properties of biomaterials to the native tissue; 3) the adaptability of the degradation properties of biomaterials to the new tissue formation. The concept of bioadaptability emphasizes both the material's characteristics and biological aspects within a certain micro-environment and molecular mechanism. It may provide new inspiration to uncover the interaction mechanism of biomaterials and tissues, to foster the new ideas of functionalization of biomaterials and to investigate the fundamental issues during the tissue repair process by biomaterials. Furthermore, designing biomaterials with such bioadaptability would open a new door for repairing and regenerating organs or tissues. In this review, we summarized the works in recent years on the bioadaptability of biomaterials for tissue repair applications.

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期刊信息
  • 《材料科学技术学报:英文版》
  • 中国科技核心期刊
  • 主管单位:中国科协
  • 主办单位:中国金属学会
  • 主编:
  • 地址:中国沈阳文化路72号
  • 邮编:110016
  • 邮箱:
  • 电话:024-83978208
  • 国际标准刊号:ISSN:1005-0302
  • 国内统一刊号:ISSN:21-1315/TG
  • 邮发代号:
  • 获奖情况:
  • 国家“双百”期刊
  • 国内外数据库收录:
  • 俄罗斯文摘杂志,美国化学文摘(网络版),荷兰文摘与引文数据库,美国工程索引,美国剑桥科学文摘,美国科学引文索引(扩展库),日本日本科学技术振兴机构数据库,中国中国科技核心期刊
  • 被引量:474