中文摘要：

Biocompatible 和可被细菌破坏的镁(Mg ) 基于金属为使用吸引了大兴趣在矫形植入并且设备。有或没有涂层显示出的微弧的氧化(毛)把那 Mg 基于我们的以前的学习房间在 Mg 的降级期间由于 pH 的增加珍视的肿瘤上的明显的细胞毒素的效果，这研究进一步评估了 Mg 和毛的细胞毒素的效果 osteosarcoma ( MG-63 )上的涂的 Mg 由通过扫描电子显微镜的观察分析房间粘附，形态学和数字的房间，以及实时/死了的染色喂奶脱氢酶( LDH )活动并且 4 ， 6-diamidino-2-phenylindole (结果显示与钛相比， Mg 能强烈在裸体 Mg 的表面上禁止 MG-63 的房间坚持，形态学和数字，而涂的 Mg 在 MG-63 房间上看了相对弱细胞毒素的效果的毛，期望那镁与合适的涂层基于金属能被设计在临床的实践作为肿瘤修复术被使用。

英文摘要：

Biocompatible and biodegradable magnesium （Mg） based metals have attracted great interest for use in orthopedic implants and devices. Based on our previous study that Mg with and without micro-arc oxidation （MAO） coating showed obvious cytotoxic effect on tumor cells due to the increase of pH value during the degradation of Mg, this study further evaluated the cytotoxic effect of Mg and MAO coated Mg on osteosarcoma （MG-63） cells by analyzing the cell adhesion, morphology and number through observation of scanning electron microscope, as well as live/dead staining, lactate dehydrogenase （LDH） activity and 4, 6- diamidino-2-phenylindole （DAPI） assay. The results indicated that, compared to titanium, Mg could strongly inhibit the cell adherence, morphology and number of MG-63 on the surface of the naked Mg, whereas the MAO coated Mg showed relative weak cytotoxic effect on MG-63 cells, expecting that magnesium based metals with suitable coating can be designed to be applied as tumor prosthesis in the clinical practice.