目的探讨甘草泻心汤加减辅助辨治复发性口腔溃疡临床效果,以期提高治疗水平。方法选取2012年6月-2015年6月216例复发性口腔溃疡患者为研究对象,分成2组,对照组108例,予西医常规治疗,观察组108例,加用甘草泻心汤加减治疗,观察治疗后在相关指标变化。结果对照组治愈率25%、总有效率78.7%;观察组治愈率37.04%、总有效率90.74%,2组比较差异有统计学意义(P〈0.05);对照组6、12、18、24个月复发率分别为30.56%、46.3%、59.26%、76.85%,观察组6、12、18、24个月复发率分别为9.26%、17.59%、18.52%、25.93%,2组比较差异有统计学意义(P〈0.05);2组治疗后在溃疡大小、溃疡数目、溃疡充血、溃疡疼痛、烧灼感上较治疗前积分明显下降,治疗前后差异显著(P〈0.05),观察组治疗后在以上症状积分上下降较对照组治疗后更加显著(P〈0.05)。结论甘草泻心汤加减辅助治疗复发性口腔溃疡可降低复发率,改善症状,提高疗效。
Objective To explore the clinical effect of the treatment of recurrent oral ulcer with Licorice HeartDraining decoction in order to improve the therapeutic level.Methods 216 patients of recurrent oral ulcer from February 2015 to February 2016 were selected as subjects and divided into two groups,108 cases in the control group were given conventional western medicine,108 cases of the observation group,plus Licorice Heart-Draining decoction.Then,we observe the changes of relevant indicators after treatment.Results The control group is 25%,the total efficiency is 78.7%;the cure rate of the observation group is 37.04%,the total efficiency is 90.74%,the difference was statistically significant(P 0.05);the recurrence rates of control group for12,18,24 month were 30.56%,46.3%,59.26%,76.85%.The recurrence rates of observation group for 6,12,18,24 months were 9.26%,17.59%,18.52%,25.93%,the difference was statistically significant(P〈0.05);after treatment on ulcer size,number of ulcers,ulcers congestion,ulcer pain,burning sensation score was significantly decreased compared with the previous treatment,the difference was significantly(P〈0.05),the treatment of observation group was better at symptom score decreasing than the control group significantly(P〈0.05).Conclusion Modified adjuvant treatment of recurrent oral ulcers with Licorice Heart-Draining decoction can reduce the recurrence rate and improve symptoms and efficacy.