中文摘要：

目的：寻求一种简洁、有效的大鼠异位心脏移植模型，作为器官移植的实验研究方案。方法：受体手术先进行至准备缝合。供体冰块腹部降温至双腋部低温后，打开胸腔，置入冰水快速致心跳停止，单人直视下缝合。腹部模型在Ono法的基础进行改进，将改进后的腹部心脏移植与颈部心肺联合移植方法进行比较。结果：腹部模型手术成功率93．2％（68／73），颈部心肺联合模型成功率80．9％（38／47），腹部移植成功率较高（P〈0．05）。但两组的手术用时差异无统计学意义（P〉0．05）。结论：腹部心脏移植能简化手术操作步骤，增加手术成功率。但颈部心肺联合移植能提供再次移植机会。

英文摘要：

Objective ： To develop a rat model of heterotopic heart transplantation with high postoperative survival rate by using the simplified surgical technique, for further studies on transplantation immunology, pathology and organ protection. Methods： The operation on recipients went fist so that the vessels could be anastomosed right after donor＇s heart had been cut off. Donor＇s temperature decreased by saline ice cube placed in abdomen until its axillary fossa felt cold, then the thoracic cavity was opened to stop heartbeat quickly by ice physiological saline. Whole process was mainly completed by a single man without micro- scope assistance. Development of abdominal heart transplantation took place on the base of Ono＇s procedure. Developed abdominal heart transplantation was compared with cervical heart-lung transplantation. Results： The success rate of abdominal heart transplantation was up to 93.2% （68/73） versus 80.9% （38/ 47） in the cervical group（Chi-square test, P 〈0.05） . And, there＇s no significant difference between two groups in operating time （ group t-test, P 〉 0. 05 ）. Conclusion： The advantage of developed abdominal heart transplantation lies in simplifying the procedure and succeeding highly. But cervical heart-lung transplantation has a chance to undergo second grafting.